¿Esto suena natural? 1. Please pray for optimal outcome every step of the way and especially for D's health.
2. Pray for R's childcare center life and he will grow well physically, mentally and spiritually in Christ.
3. Pray that during pregnancy J will be able to cope with her works and care of D and R.
4. Pray that J can drive safely. Keep her and R safe.
5. Pray for J to take care of the ministry of the Sunday School in the church by filling the Holy Spirit.

2. Pray for R's childcare center life and that he may grow well physically, mentally and spiritually in Christ.
2. Pray for R's childcare center life and for him to grow well physically, mentally and spiritually in Christ.

3. Pray that during pregnancy J will be able to cope with work and caring for D and R.
3. Pray that during pregnancy J will be able to cope with her work and taking care of D and R.
('work'과 'her work'가 둘 다 직장입니다)

There is a difference between 'cope with work and caring for D and R', and 'cope with work and care for D and R'. In the first, 'cope with' applies to both work and the task of caring for those two people. In the second, the meaning of 'cope with' only applies to work. Both of them sound okay.

(의도하신 의미가 무엇인지 확실히 모르겠습니다) 5. Pray for J to be filled with the Holy Spirit in taking care of the ministry of the Sunday School.